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Marcel Garcia Selected Research

Mannose (D-Mannose)

7/2020The mannose 6-phosphate receptor targeted with porphyrin-based periodic mesoporous organosilica nanoparticles for rhabdomyosarcoma theranostics.
6/2019Efficient Photodynamic Therapy of Prostate Cancer Cells through an Improved Targeting of the Cation-Independent Mannose 6-Phosphate Receptor.
1/2019Mannose 6-phosphonate labelling: A key for processing the therapeutic enzyme in Pompe disease.
10/2018Efficient therapy for refractory Pompe disease by mannose 6-phosphate analogue grafting on acid α-glucosidase.
11/2016Design of Potent Mannose 6-Phosphate Analogues for the Functionalization of Lysosomal Enzymes To Improve the Treatment of Pompe Disease.
2/2016Ruthenium(ii) complex-photosensitized multifunctionalized porous silicon nanoparticles for two-photon near-infrared light responsive imaging and photodynamic cancer therapy.
5/2015Mannose-6-phosphate receptor: a target for theranostics of prostate cancer.
12/2014Two-photon excitation of porphyrin-functionalized porous silicon nanoparticles for photodynamic therapy.
11/2011Mannose-functionalized mesoporous silica nanoparticles for efficient two-photon photodynamic therapy of solid tumors.
12/2010Silicalites and Mesoporous Silica Nanoparticles for photodynamic therapy.
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Marcel Garcia Research Topics

Disease

31Neoplasms (Cancer)
07/2020 - 07/2002
28Breast Neoplasms (Breast Cancer)
03/2019 - 08/2002
5Neoplasm Metastasis (Metastasis)
11/2013 - 08/2002
3Prostatic Neoplasms (Prostate Cancer)
06/2019 - 05/2015
3Glycogen Storage Disease Type II (Pompe's Disease)
01/2019 - 11/2016
2Colorectal Neoplasms (Colorectal Cancer)
09/2012 - 02/2012
2Carcinogenesis
07/2004 - 08/2002
1Rhabdomyosarcoma
07/2020
1Melanoma (Melanoma, Malignant)
01/2017
1Muscular Diseases (Myopathy)
11/2016
1Type 2 Diabetes Mellitus (MODY)
02/2016
1Diabetes Mellitus
02/2016
1Rare Diseases (Rare Disease)
08/2012
1Retinoblastoma (Glioblastoma, Retinal)
08/2012
1Phototoxic Dermatitis (Phototoxicity)
12/2010
1Cicatrix (Scar)
05/2006

Drug/Important Bio-Agent (IBA)

12Mannose (D-Mannose)IBA
07/2020 - 05/2006
111-phenyl-3,3-dimethyltriazene (PDT)IBA
07/2020 - 03/2009
8Silicon Dioxide (Silica)FDA LinkGeneric
06/2019 - 11/2011
6Cathepsin DIBA
01/2019 - 08/2002
6Pharmaceutical PreparationsIBA
09/2016 - 02/2012
4PorphyrinsIBA
07/2020 - 05/2013
4Peptide Hydrolases (Proteases)FDA Link
01/2019 - 08/2002
4pepstatin (pepstatin A)IBA
01/2019 - 10/2013
4EnzymesIBA
01/2019 - 05/2006
4Estrogen ReceptorsIBA
08/2016 - 07/2004
4Estrogens (Estrogen)FDA Link
11/2012 - 07/2004
3GlucosidasesIBA
10/2018 - 02/2016
3Photosensitizing Agents (Photosensitizers)IBA
10/2017 - 02/2012
3Doxorubicin (Adriamycin)FDA LinkGeneric
09/2016 - 05/2015
3Estrogen Receptor Modulators (Antiestrogen)IBA
08/2016 - 01/2008
3LigandsIBA
07/2016 - 03/2008
3SiliconIBA
06/2016 - 05/2013
3CamptothecinIBA
12/2013 - 02/2012
3Estrogen Receptor alphaIBA
11/2012 - 03/2008
2CationsIBA
06/2019 - 05/2015
2AcidsIBA
10/2018 - 11/2016
2Bortezomib (Velcade)FDA Link
08/2016 - 11/2012
2Proteasome InhibitorsIBA
08/2016 - 11/2012
2mannose-6-phosphateIBA
06/2016 - 07/2002
2JMV4463IBA
02/2016 - 10/2013
2GoldIBA
01/2016 - 01/2015
2IGF Type 2 Receptor (Insulin-Like-Growth-Factor II Receptor)IBA
05/2015 - 05/2006
2Volatile Oils (Essential Oils)IBA
04/2014 - 02/2014
2Aspartic Acid ProteasesIBA
11/2013 - 10/2013
2Proteins (Proteins, Gene)FDA Link
11/2012 - 07/2002
1Biological ProductsIBA
07/2020
1Dendrimers (Dendrons)IBA
03/2019
1Peptides (Polypeptides)IBA
01/2019
1imidazopyridineIBA
01/2017
1AT 760IBA
09/2016
1Fulvestrant (Faslodex)FDA Link
08/2016
1TamoxifenFDA LinkGeneric
08/2016
1Hydroxyl RadicalIBA
08/2016
1benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA
08/2016
1Alkynes (Acetylenes)IBA
07/2016
1CopperIBA
07/2016
1AzidesIBA
07/2016
1AcarboseFDA LinkGeneric
02/2016
1Synthetic DrugsIBA
02/2016
1RutheniumIBA
02/2016
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
02/2016
1statineIBA
02/2016
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
02/2016
1Small Interfering RNA (siRNA)IBA
09/2015
1DisulfidesIBA
08/2015
1rhodamine BIBA
07/2015
1LectinsIBA
05/2015
1Mannose ReceptorIBA
12/2014
1Phosphotransferases (Kinase)IBA
03/2014
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
11/2013
12'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
11/2013
1Plasminogen Activators (Plasminogen Activator)IBA
11/2013
1DipeptidesIBA
10/2013
1ProdrugsIBA
09/2013
1Fluorouracil (Carac)FDA LinkGeneric
09/2013
1CateninsIBA
11/2012
1Desmoplakins (Desmoplakin)IBA
11/2012
1PlakophilinsIBA
11/2012
1DesmocollinsIBA
11/2012
1Cyclin-Dependent Kinases (cdk Proteins)IBA
11/2012
1Hyaluronic Acid (Hyaluronan)IBA
09/2012
1CarbohydratesIBA
08/2012
1Galactose (Galactopyranose)FDA LinkGeneric
02/2012
1galactose receptorIBA
02/2012
1Cyclin-Dependent Kinase Inhibitor p21IBA
03/2008
1DNA (Deoxyribonucleic Acid)IBA
03/2008
1Cell Surface ReceptorsIBA
06/2006
1Phosphates (Orthophosphate)IBA
05/2006
1Transforming Growth Factor beta (TGF-beta)IBA
05/2006
1Proliferating Cell Nuclear Antigen (PCNA)IBA
08/2002
1AgarIBA
08/2002
1matrigelIBA
08/2002

Therapy/Procedure

13Therapeutics
10/2018 - 08/2002
12Photochemotherapy (Photodynamic Therapy)
06/2019 - 11/2011
3Precision Medicine
07/2020 - 05/2015
1Enzyme Therapy
01/2019
1Enzyme Replacement Therapy
10/2018
1Lasers (Laser)
09/2016
1Nanospheres
01/2016